Docuset (Tablet)

Unit Price:
৳ 1.99


(30’s pack: ৳ 59.66)


Indications

Docusate is indicated in Constipation, Bowel evacuation, Softening of ear wax, Constipation

Therapeutic Class

Stool softener

Pharmacology

Docusate acts primarily by increasing the penetration of fluid into the faeces. It may also have effects on intestinal fluid secretion, and probably act both as stimulant and faecal softening agent. It also softens ear wax through penetration into the dry matrix of the ceruminous mass, reducing it into semi-solid debris.

Dosage & Administration

Constipation:

  • Adult: 50-300 mg daily in divided doses. Max: 500 mg daily.
  • Child: ≥12 yr Same as adult dose.

Bowel evacuation:

  • Adult: As adjunct to abdominal radiological procedures: 400 mg given with barium meal.
  • Child: ≥12 yr Same as adult dose.

Interaction

May enhance GI uptake of other drugs (e.g. liquid paraffin). May increase effects of anthraquinone laxatives. Increased incidence of adverse effects in GI mucosa with aspirin.

Contraindications

Presence of abdominal pain, nausea, vomiting, intestinal obstruction. Perforation of ear drum or ear inflammation (otic).

Side Effects

Anorectal pain or bleeding (rectal). Rarely, diarrhoea, abdominal cramps, nausea, skin rash.

Pregnancy & Lactation

Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Precautions

Rectal admin in patient with haemorrhoids or anal fissures. Children. Pregnancy and lactation.

Overdose Effects

Symptoms: Oral: Excessive loss of water and electrolytes. Otic: Skin irritation.

Management: Oral: Encourage patient to drink plenty of fluid. Replenish electrolyte loss where appropriate. Otic: Symptomatic treatment.

Storage Conditions

Store between 15-30° C. Protect from freezing, heat, humidity and light.

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