Peflacine (Tablet)
Indications
Pefloxacin is indicated for the treatment of the following infections caused by sensitive bacteria.
Severe systemic infection: Septicaemia, bacteraemia, peritonitis, infections in immunosuppressed patients with haematological or solid tumors and in patients in intensive care unit with specific problems such as infected burns.
Urinary tract infection: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis, epididymitis.
Respiratory tract infection : Lobar and bronchopneumonia, acute and chronic bronchitis, acute exacerbation of cystic fibrosis, bronchiectasis, empyema.
Gastrointestinal infection: Enteric fever, infective diarrhoea.
Infections of the biliary system: Cholangitis, cholecystitis, empyema of the gall bladder.
Skin and soft tissue infection: Infected ulcers, wound infections, abscesses, cellulitis, otitis externa, erysipelas, infected burns.
Eye, ear, nose and throat infection: Otitis media, sinusitis, mastoiditis, tonsillitis.
Intra abdominal infection: Peritonitis, intra abdominal abscesses.
Bone and joint infection: Osteomyelitis, septic arthritis.
Pelvic infection: Salpingitis, endometritis, pelvic inflammatory diseases.
Gonorrhoea: Including urethral, rectal and pharyngeal gonorrhoea caused by β lactamase producing organisms or organisms moderately sensitive to penicillin.
Therapeutic Class
Pharmacology
Dosage & Administration
IV Infusion: 400 mg in 100 ml of 5% dextrose slow infusion over 1 hr bid.
Interaction
Contraindications
Side Effects
Central nervous system (CNS): Dizziness, headache, tiredness, confusion, convulsions. Hypersensitivity reactions : skin rashes, pruritus. The other reactions have also been reported are joint pain, mild photosensitivity and thrombocytopenia (at doses of 1600 mg daily).